It is a well known fact that medication side-effects place a huge burden on our healthcare system. I believe that the majority of these problems can be averted by identifying concerns early. Pharmacists are a great resource to help identify and manage medication-related problems. I have established the practice of doing follow-up phone calls with patients at my pharmacy whenever they start a new medication. I have seen the benefit that this has had with my patients and have been able to identify therapy problems and help resolve them. Unfortunately, this is not standard practice because of the limited time pharmacists have to engage in such activities. Innovators who choose this challenge will develop an automated SMS “chat bot” follow up system that can be programmed to follow up with patients that start new medications. The monitoring parameters and questions would be relevant and specific to each medication based on a clinical algorithm.